Alice J. M. Borst

Bioisosteric Replacements of the Pyrazole Moiety of Rimonabant:  Synthesis, Biological Properties, and Molecular Modeling Investigations of Thiazoles, Triazoles, and Imidazoles as Potent and Selective CB₁Cannabinoid Receptor Antagonists

Jos H.M. Lange, Herman H. van Stuivenberg, Hein K. A. C. Coolen et al. · Journal of Medicinal Chemistry · 2004 · 177 citations · Full text

Pyrazole Series, Organic Chemistry, Pharmacotherapy +19

Design, Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel Tacrine Derivatives with a Combination of Acetylcholinesterase Inhibition and Cannabinoid CB₁Receptor Antagonism

Jos H.M. Lange, Hein K. A. C. Coolen, Martina A.W. van der Neut et al. · Journal of Medicinal Chemistry · 2010 · 61 citations · Full text

<i>N</i>′-(Arylsulfonyl)pyrazoline-1-carboxamidines as Novel, Neutral 5-Hydroxytryptamine 6 Receptor (5-HT₆R) Antagonists with Unique Structural Features

Arnold van Loevezijn, Jennifer Venhorst, Wouter Bakker et al. · Journal of Medicinal Chemistry · 2011 · 44 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +20

Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB2 receptor antagonists with high binding efficiencies

Jos H.M. Lange, Martina A.W. van der Neut, Henri C. Wals et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 27 citations · Full text

Cannabis Use, Medicinal Chemistry, Drug Target +11

Fluvoxamine: metabolic fate in animals.

H. M. Ruijten, H. de Bree, Alice J. M. Borst et al. · Drug Metabolism and Disposition · 1984 · 26 citations