Thomas P. Howard

Mutational processes shape the landscape of TP53 mutations in human cancer

Andrew O. Giacomelli, Xiaoping Yang, Robert Lintner et al. · Nature Genetics · 2018 · 566 citations · Full text

Genome Instability, Somatic Variant, Tumor Heterogeneity +10

SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2

Kimberly H. Kim, Woojin Kim, Thomas P. Howard et al. · Nature Medicine · 2015 · 408 citations · Full text

Tumor Biology, Systems Biology, Oncogenic Agent +9

BRD9 defines a SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors

Xiaofeng Wang, Su Wang, Emma C. Troisi et al. · Nature Communications · 2019 · 209 citations · Full text

A first-generation pediatric cancer dependency map

Neekesh V. Dharia, Guillaume Kugener, Lillian M. Guenther et al. · Nature Genetics · 2021 · 151 citations · Full text

Medicine, Pediatrics, Cancer Registration +4

MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors

Thomas P. Howard, Taylor E. Arnoff, Melinda R. Song et al. · Cancer Research · 2019 · 69 citations · Full text