Biologically informed deep neural network for prostate cancer discovery

Haitham Elmarakeby, Justin H. Hwang, Rand Arafeh, +11

Nature

Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

Sylvan C. Baca, David Y. Takeda, Ji-Heui Seo, +38

Nature Communications

MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors

Thomas P. Howard, Taylor E. Arnoff, Melinda R. Song, +25

Cancer Research

SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization

Chao Dai, Jonathan Rennhack, Taylor E. Arnoff, +19

Cell Reports

CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies

Justin H. Hwang, Rand Arafeh, Ji-Heui Seo, +18

eLife

<i>MDM2/MDM4</i> amplification and <i>CDKN2A</i> deletion in metastatic melanoma and glioblastoma multiforme may have implications for targeted therapeutics and immunotherapy.

Taylor E. Arnoff, Wafik S. El‐Deiry

PubMed

Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine

Thomas P. Howard, Elaine M. Oberlick, Matthew G. Rees, +22

Clinical Cancer Research

Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer

Kimberly R. Hagel, Rand Arafeh, Sydney Gang, +7

Cancer Research

Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

Sylvan C. Baca, David Y. Takeda, Ji-Heui Seo, +38