David Y. Takeda

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles

Aravind Subramanian, Rajiv Narayan, Steven M. Corsello et al. · Cell · 2017 · 3.5K citations · Full text

Network Science, Engineering, Data Science +12

Mutational processes shape the landscape of TP53 mutations in human cancer

Andrew O. Giacomelli, Xiaoping Yang, Robert Lintner et al. · Nature Genetics · 2018 · 566 citations · Full text

Genome Instability, Somatic Variant, Tumor Heterogeneity +10

The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis

Mark M. Pomerantz, Fugen Li, David Y. Takeda et al. · Nature Genetics · 2015 · 465 citations · Full text

Urology, Oncology, Endocrine-related Cancer +9

A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer

David Y. Takeda, Sándor Spisák, Ji-Heui Seo et al. · Cell · 2018 · 328 citations · Full text

Androgen Receptor, Urology, Somatically Acquired Enhancer +8

Prostate cancer reactivates developmental epigenomic programs during metastatic progression

Mark M. Pomerantz, Xintao Qiu, Yanyun Zhu et al. · Nature Genetics · 2020 · 271 citations · Full text

Developmental Biology, Epigenomics, Cancer Genomics +3