Andrew O. Giacomelli

Mutational processes shape the landscape of TP53 mutations in human cancer

Andrew O. Giacomelli, Xiaoping Yang, Robert Lintner et al. · Nature Genetics · 2018 · 566 citations · Full text

Genome Instability, Somatic Variant, Tumor Heterogeneity +10

Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells

Eleftherios Sachlos, Ruth M. Risueño, Sarah Laronde et al. · Cell · 2012 · 452 citations · Full text

Drug Targeting, Medicine, Stem Cell Toxicology +9

A dominant-negative effect drives selection of <i>TP53</i> missense mutations in myeloid malignancies

Steffen Boettcher, Peter G. Miller, Rohan Sharma et al. · Science · 2019 · 416 citations · Full text

Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer

Mohamed E. Abazeed, Drew Adams, Kristen E. Hurov et al. · Cancer Research · 2013 · 130 citations · Full text

An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer

Ji Li, Peter S. Choi, Christine L. Chaffer et al. · eLife · 2018 · 123 citations · Full text

Emt Gene Signatures, Breast Oncology, Mrna Precursors +19