Neekesh V. Dharia

Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

Robin M. Meyers, Jordan Bryan, James M. McFarland et al. · Nature Genetics · 2017 · 2.1K citations · Full text

Genetics, Genetic Engineering, Crispr–cas9 Essentiality Screens +7

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

Matthias Rottmann, Case W. McNamara, Bryan K. S. Yeung et al. · Science · 2010 · 1.2K citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Science +15

Imaging of <i>Plasmodium</i> Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

Stephan Meister, David Plouffe, Kelli Kuhen et al. · Science · 2011 · 347 citations · Full text

Antiparasitic Agent, Malaria, Pathology +16

Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry

Adam D. Durbin, Mark W. Zimmerman, Neekesh V. Dharia et al. · Nature Genetics · 2018 · 291 citations · Full text

Transcriptional Regulation, Systems Biology, Glioma +7

Single-Agent Divarasib (GDC-6036) in Solid Tumors with a <i>KRAS</i> G12C Mutation

Adrian G. Sacher, Patricia LoRusso, Manish R. Patel et al. · New England Journal of Medicine · 2023 · 256 citations · Full text