Guillaume Kugener

Genetic and transcriptional evolution alters cancer cell line drug response

Uri Ben‐David, Benjamin A. Siranosian, Gavin Ha et al. · Nature · 2018 · 890 citations · Full text

Tumor Heterogeneity, Medicine, Oncogenic Agent +9

Mitochondrial metabolism promotes adaptation to proteotoxic stress

Peter Tsvetkov, Alexandre Detappe, Kai Cai et al. · Nature Chemical Biology · 2019 · 577 citations · Full text

Mitochondrial Biogenesis, Mitochondrial Function, Physiology +5

Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines

Joshua M. Dempster, Jordan Rossen, Mariya Kazachkova et al. · 2019 · 423 citations · Full text

Project Achilles, Engineering, Genetic Dependencies +21

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

James M. McFarland, Zandra V. Ho, Guillaume Kugener et al. · Nature Communications · 2018 · 406 citations · Full text

Genetics, Large-scale Rnai Screens, Transcriptomics Technology +22

A first-generation pediatric cancer dependency map

Neekesh V. Dharia, Guillaume Kugener, Lillian M. Guenther et al. · Nature Genetics · 2021 · 151 citations · Full text

Medicine, Pediatrics, Cancer Registration +4