Joshua M. Dempster

Genetic and transcriptional evolution alters cancer cell line drug response

Uri Ben‐David, Benjamin A. Siranosian, Gavin Ha et al. · Nature · 2018 · 948 citations · Full text

Medicine, Genetics, Oncology +13

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

James M. McFarland, Zandra V. Ho, Guillaume Kugener et al. · Nature Communications · 2018 · 434 citations · Full text

Medicine, Cancer Biology, Genetics +12

Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines

Joshua M. Dempster, Jordan Rossen, Mariya Kazachkova et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 429 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects

Joshua M. Dempster, Isabella Boyle, Francisca Vázquez et al. · Genome biology · 2021 · 411 citations · Full text

Life Sciences, Cell Biology, Genetics +14

Integrated cross-study datasets of genetic dependencies in cancer

Clare Pacini, Joshua M. Dempster, Isabella Boyle et al. · Nature Communications · 2021 · 339 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16