Concepedia

Giovanni Cianchetta

GC

16

Publications

1.8K

Citations

15

H-Index

2004

Active since

Affiliations

Agios Pharmaceuticals (United States)(Current)

Lexicon Pharmaceuticals (United States)

Molecular Discovery (United Kingdom)

University of Perugia

Inserm

Giovanni Cianchetta is an author at Agios Pharmaceuticals (United States) specializing in medicine, biochemistry, and drug discovery.

Top concepts

Publications per year

2004–2019

16

Publications

16

AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic <i>IDH2</i> Mutations

Katharine Yen, Jeremy Travins, Fang Wang et al. · Cancer Discovery · 2017 · 444 citations · Full text

Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers

Janeta Popovici-Müller, René M. Lemieux, Erin Artin et al. · ACS Medicinal Chemistry Letters · 2018 · 422 citations · Full text

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Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase

Anil K. Padyana, Lei Jin, Giovanni Cianchetta et al. · Nature Communications · 2019 · 146 citations · Full text

AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiency

Charles Kung, Jeff Hixon, Penelope A. Kosinski et al. · Blood · 2017 · 123 citations · Full text

Recurrent Germline DLST Mutations in Individuals with Multiple Pheochromocytomas and Paragangliomas

Laura Remacha, David Pirman, Christopher E. Mahoney et al. · The American Journal of Human Genetics · 2019 · 91 citations · Full text

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