Janeta Popovici-Müller

An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells

Dan Rohle, Janeta Popovici-Müller, Nicolaos Palaskas et al. · Science · 2013 · 1.2K citations

Medicine, Cancer Biology, Oncology +17

Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation

Fang Wang, Jeremy Travins, Byron DeLaBarre et al. · Science · 2013 · 797 citations

Medicine, Cancer Biology, Oncology +10

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer

Supriya K. Saha, Christine A. Parachoniak, Krishna S. Ghanta et al. · Nature · 2014 · 469 citations

Medicine, Cancer Biology, Molecular Biology +14

Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers

Janeta Popovici-Müller, René M. Lemieux, Erin Artin et al. · ACS Medicinal Chemistry Letters · 2018 · 444 citations · Full text

Medicine, Molecular Biology, Oncology +14

Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG <i>in Vivo</i>

Janeta Popovici-Müller, Jeffrey O. Saunders, Francesco G. Salituro et al. · ACS Medicinal Chemistry Letters · 2012 · 197 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6