Graham Johnson

Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels

Valentin K. Gribkoff, John E. Starrett, Steven I. Dworetzky et al. · Nature Medicine · 2001 · 311 citations

Life Sciences, Neurology, Neuroscience +16

Substituted 2-Benzothiazolamines as Sodium Flux Inhibitors: Quantitative Structure-Activity Relationships and Anticonvulsant Activity

Sheryl J. Hays, Michael J. Rice, Daniel F. Ortwine et al. · Journal of Pharmaceutical Sciences · 1994 · 108 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

Synthesis and structure–activity relationship of novel benzoxazole derivatives as melatonin receptor agonists

Li‐Qiang Sun, Jie Chen, Marc A. Bruce et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 89 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Preclinical validation of a potent γ-secretase modulator for Alzheimer’s disease prevention

Kevin D. Rynearson, Moorthi Ponnusamy, Olga Prikhodko et al. · The Journal of Experimental Medicine · 2021 · 72 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists

Daniel F. Ortwine, Thomas C. Malone, Christopher F. Bigge et al. · Journal of Medicinal Chemistry · 1992 · 64 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13