Thomas O. Daniel

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

Yosef Yarden, J A Escobedo, Wun-Jing Kuang et al. · Nature · 1986 · 1.2K citations

Thrombopoiesis, Signal Transduction, Developmental Biology +10

A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase

Mary E. Matyskiela, Gang Lu, Takumi Ito et al. · Nature · 2016 · 628 citations

Protein Function, Signal Transduction, Cell Regulation +10

Immunomodulatory agents lenalidomide and pomalidomide co‐stimulate <scp>T</scp> cells by inducing degradation of <scp>T</scp> cell repressors <scp>I</scp> karos and <scp>A</scp> iolos via modulation of the <scp>E</scp> 3 ubiquitin ligase complex <scp>CRL</scp> 4 <scp> ^CRBN </scp>

Anita K. Gandhi, Jian Kang, Courtney G. Havens et al. · British Journal of Haematology · 2013 · 611 citations · Full text

The CXC Chemokine Receptor 2, CXCR2, Is the Putative Receptor for ELR+ CXC Chemokine-Induced Angiogenic Activity

Christina Addison, Thomas O. Daniel, Marie D. Burdick et al. · The Journal of Immunology · 2000 · 570 citations · Full text

Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs

Philip P. Chamberlain, Antonia Lopez‐Girona, Karen Miller et al. · Nature Structural & Molecular Biology · 2014 · 499 citations

Molecular Pharmacology, Natural Sciences, Molecular Biology +6