Concepedia

Courtney G. Havens

CG

15

Publications

2.1K

Citations

14

H-Index

2000

Active since

Affiliations

Harvard University(Current)

University of Oxford

Bristol-Myers Squibb (Switzerland)

Massachusetts General Hospital

Howard Hughes Medical Institute

Courtney G. Havens is an author at Harvard University specializing in medicine, molecular biology, and cell biology.

Top concepts

Publications per year

2000–2020

15

Publications

15

Immunomodulatory agents lenalidomide and pomalidomide co‐stimulate <scp>T</scp> cells by inducing degradation of <scp>T</scp> cell repressors <scp>I</scp> karos and <scp>A</scp> iolos via modulation of the <scp>E</scp> 3 ubiquitin ligase complex <scp>CRL</scp> 4 <scp> <sup>CRBN</sup> </scp>

Anita K. Gandhi, Jian Kang, Courtney G. Havens et al. · British Journal of Haematology · 2013 · 611 citations · Full text

CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase

Richard C. Centore, Courtney G. Havens, Amity L. Manning et al. · Molecular Cell · 2010 · 222 citations · Full text

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Rate of CRL4CRBN substrate Ikaros and Aiolos degradation underlies differential activity of lenalidomide and pomalidomide in multiple myeloma cells by regulation of c-Myc and IRF4

Chad C. Bjorklund, Ling Lu, Jian Kang et al. · Blood Cancer Journal · 2015 · 211 citations · Full text

Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma

Joshua D. Hansen, Matthew Correa, Mark A. Nagy et al. · Journal of Medicinal Chemistry · 2020 · 204 citations · Full text

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CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL

Patrick R. Hagner, Hon‐Wah Man, Celia Fontanillo et al. · Blood · 2015 · 197 citations · Full text

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