Caroline Kurtz

Development of a synthetic live bacterial therapeutic for the human metabolic disease phenylketonuria

Vincent M. Isabella, Binh Ha, Mary Joan Castillo et al. · Nature Biotechnology · 2018 · 548 citations

Biosynthesis, Engineering, Biotechnology +6

An engineered <i>E. coli</i> Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans

Caroline Kurtz, Yves Millet, Marja Puurunen et al. · Science Translational Medicine · 2019 · 366 citations

The Effect of Psyllium Husk on Intestinal Microbiota in Constipated Patients and Healthy Controls

Jonna Jalanka, Giles Major, Kathryn Murray et al. · International Journal of Molecular Sciences · 2019 · 198 citations · Full text

The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1.

Caroline Kurtz, Erin O’Toole, Steven M. Christensen et al. · The Journal of Immunology · 1990 · 168 citations

Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study

Marja Puurunen, Jerry Vockley, Shawn Searle et al. · Nature Metabolism · 2021 · 146 citations

Engineering, Medicine, First-in-human Phase 1/2A +8