Concepedia

Dorothy Levorse

DL

23

Publications

1K

Citations

17

H-Index

1993

Active since

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

United States Military Academy

Memorial Sloan Kettering Cancer Center

Tri-Institutional PhD Program in Chemical Biology

University of California, Irvine

Dorothy Levorse is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicine, pharmacology, and drug discovery.

ORCID

Top concepts

Publications per year

1993–2022

23

Publications

23

(2<i>S</i>,3<i>S</i>)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-<i>N,N</i>-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-<i>a</i>]- pyridin-6-ylphenyl)butanamide:  A Selective α-Amino Amide Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

Scott D. Edmondson, Anthony Mastracchio, Robert J. Mathvink et al. · Journal of Medicinal Chemistry · 2006 · 121 citations · Full text

Difluoroethylamines as an amide isostere in inhibitors of cathepsin K

Élise Isabel, Christophe Mellon, Michael J. Boyd et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 111 citations · Full text

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Discovery of Vibegron: A Potent and Selective β<sub>3</sub>Adrenergic Receptor Agonist for the Treatment of Overactive Bladder

Scott D. Edmondson, Cheng Zhu, Nam Fung Kar et al. · Journal of Medicinal Chemistry · 2015 · 101 citations · Full text

Ionization Behavior of Amino Lipids for siRNA Delivery: Determination of Ionization Constants, SAR, and the Impact of Lipid p<i>K</i><sub>a</sub> on Cationic Lipid−Biomembrane Interactions

Jingtao Zhang, Haihong Fan, Dorothy Levorse et al. · Langmuir · 2011 · 85 citations

Inhibition of Stromelysin-1 (MMP-3) by P<sub>1</sub>‘-Biphenylylethyl Carboxyalkyl Dipeptides

Craig K. Esser, Robert L. Bugianesi, Charles G. Caldwell et al. · Journal of Medicinal Chemistry · 1997 · 65 citations · Full text

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