Scott D. Edmondson

Dipeptidyl Peptidase IV Inhibition for the Treatment of Type 2 Diabetes

George R. Lankas, Barbara Leiting, Ranabir Sinha Roy et al. · Diabetes · 2005 · 491 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +12

Total Synthesis of Spirotryprostatin A, Leading to the Discovery of Some Biologically Promising Analogues

Scott D. Edmondson, Samuel J. Danishefsky, Laura Sepp‐Lorenzino et al. · Journal of the American Chemical Society · 1999 · 463 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD5305): A PARP1–DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs

Jeffrey W. Johannes, Amber Balazs, Derek Barratt et al. · Journal of Medicinal Chemistry · 2021 · 140 citations · Full text

Life Sciences, Medicinal Chemistry, Oncology +13

(2<i>S</i>,3<i>S</i>)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-<i>N,N</i>-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-<i>a</i>]- pyridin-6-ylphenyl)butanamide:  A Selective α-Amino Amide Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

Scott D. Edmondson, Anthony Mastracchio, Robert J. Mathvink et al. · Journal of Medicinal Chemistry · 2006 · 121 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Crystal Structure of Human Phosphodiesterase 3B:  Atomic Basis for Substrate and Inhibitor Specificity

Giovanna Scapin, Sangita B. Patel, Jeffrey P. Varnerin et al. · Biochemistry · 2004 · 119 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14