Laura Sepp‐Lorenzino

CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis

Julian D. Gillmore, Ed Gane, Jörg Täubel et al. · New England Journal of Medicine · 2021 · 1.5K citations · Full text

Total Synthesis of Spirotryprostatin A, Leading to the Discovery of Some Biologically Promising Analogues

Scott D. Edmondson, Samuel J. Danishefsky, Laura Sepp‐Lorenzino et al. · Journal of the American Chemical Society · 1999 · 459 citations

Biologically Promising Analogues, Bioorganic Chemistry, Heterocycle Chemistry +16

Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90

Christine Schneider, Laura Sepp‐Lorenzino, Elmar Nimmesgern et al. · Proceedings of the National Academy of Sciences · 1996 · 407 citations · Full text

Protein Assembly, Molecular Regulation, Molecular Biology +18

A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines.

Laura Sepp‐Lorenzino, Zhuang Ma, Elaine Rands et al. · PubMed · 1995 · 384 citations

Chemoprevention Strategy, Protein Transferase, Cancer Biology +17

Micro RNA 145 Targets the Insulin Receptor Substrate-1 and Inhibits the Growth of Colon Cancer Cells

Bin Shi, Laura Sepp‐Lorenzino, Marco di Prisco et al. · Journal of Biological Chemistry · 2007 · 354 citations · Full text

Cancer Research, Type 1, Insulin Receptor Substrate-1 +14