Jeffrey W. Johannes

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia

Adriana E. Tron, Matthew A. Belmonte, Ammar Adam et al. · Nature Communications · 2018 · 486 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Photoredox Mediated Nickel Catalyzed Cross-Coupling of Thiols With Aryl and Heteroaryl Iodides via Thiyl Radicals

Martins S. Oderinde, Mathieu Frenette, Daniel Robbins et al. · Journal of the American Chemical Society · 2016 · 453 citations

Natural Sciences, Chemistry, Catalysis +15

Current and Future Roles of Artificial Intelligence in Medicinal Chemistry Synthesis

Thomas J. Struble, Juan C. Alvarez, Scott P. Brown et al. · Journal of Medicinal Chemistry · 2020 · 250 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Highly Chemoselective Iridium Photoredox and Nickel Catalysis for the Cross‐Coupling of Primary Aryl Amines with Aryl Halides

Martins S. Oderinde, Natalie H. Jones, Antoine Juneau et al. · Angewandte Chemie International Edition · 2016 · 211 citations

Natural Sciences, Chemistry, Medicinal Chemistry +17

Preclinical Characterization of AZD5305, A Next-Generation, Highly Selective PARP1 Inhibitor and Trapper

Giuditta Illuzzi, Anna D. Staniszewska, Sonja J. Gill et al. · Clinical Cancer Research · 2022 · 171 citations · Full text

Medicine, Oncology, Pharmacology +13