Concepedia

Juan C. Alvarez

JC

Statistics

Publications

10

Citations

946

H-Index

10

Active since

1990

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

University of California, San Francisco

Juan C. Alvarez is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in pharmacy, medicinal chemistry, and drug discovery.

ORCID

Publications per year

1990–2021

10

Publications

10

Structure-based design of nonpeptide inhibitors specific for the human immunodeficiency virus 1 protease.

Renée L. DesJarlais, George Seibel, Irwin D. Kuntz et al. · Proceedings of the National Academy of Sciences · 1990 · 254 citations · Full text

, , +16

Current and Future Roles of Artificial Intelligence in Medicinal Chemistry Synthesis

Thomas J. Struble, Juan C. Alvarez, Scott P. Brown et al. · Journal of Medicinal Chemistry · 2020 · 250 citations · Full text

, , +17

ALKS 4230: a novel engineered IL-2 fusion protein with an improved cellular selectivity profile for cancer immunotherapy

Jared E. Lopes, Jan L. Fisher, Heather Flick et al. · Journal for ImmunoTherapy of Cancer · 2020 · 138 citations · Full text

, , +17

Pharmacophore‐based molecular docking to account for ligand flexibility

Diane Joseph‐McCarthy, Bert E. Thomas, Michael Belmarsh et al. · Proteins Structure Function and Bioinformatics · 2003 · 80 citations

, , +14

Experimental Error, Kurtosis, Activity Cliffs, and Methodology: What Limits the Predictivity of Quantitative Structure–Activity Relationship Models?

Robert P. Sheridan, Prabha Karnachi, Matthew Tudor et al. · Journal of Chemical Information and Modeling · 2020 · 64 citations

, , +16

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