Kouhei Asano

Discovery of a novel B-cell lymphoma 6 (BCL6)–corepressor interaction inhibitor by utilizing structure-based drug design

Takeshi Yasui, Takeshi Yamamoto, Nozomu Sakai et al. · Bioorganic & Medicinal Chemistry · 2017 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +14

Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship

Kotaro Sakamoto, Satoshi Sogabe, Yusuke Kamada et al. · Biochemical and Biophysical Research Communications · 2016 · 36 citations

Pharmacy, Biochemistry, Medicinal Chemistry +14

Coenzyme A: Diacylglycerol acyltransferase 1 inhibitor ameliorates obesity, liver steatosis, and lipid metabolism abnormality in KKAy mice fed high-fat or high-carbohydrate diets

Toshihiro Yamamoto, Hiroshi Yamaguchi, Hiroshi Miki et al. · European Journal of Pharmacology · 2010 · 33 citations

Life Sciences, Biochemistry, Pharmacology +17

Design, synthesis, and structure–activity relationships of dihydrofuran-2-one and dihydropyrrol-2-one derivatives as novel benzoxazin-3-one-based mineralocorticoid receptor antagonists

Tomoaki Hasui, Taiichi Ohra, Norio Ohyabu et al. · Bioorganic & Medicinal Chemistry · 2013 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of 6-[5-(4-fluorophenyl)-3-methyl-pyrazol-4-yl]-benzoxazin-3-one derivatives as novel selective nonsteroidal mineralocorticoid receptor antagonists

Tomoaki Hasui, Norio Ohyabu, Taiichi Ohra et al. · Bioorganic & Medicinal Chemistry · 2014 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7