Concepedia

Discovery of 6-[5-(4-fluorophenyl)-3-methyl-pyrazol-4-yl]-benzoxazin-3-one derivatives as novel selective nonsteroidal mineralocorticoid receptor antagonists

Tomoaki Hasui, Norio Ohyabu, Taiichi Ohra, Koji Fuji, Takahiro Sugimoto, Jun Fujimoto, Kouhei Asano, Masato Oosawa, Sachiko Shiotani, Nobuhiro Nishigaki,

Bioorganic & Medicinal Chemistry · 2014 · 27 citations · 19 references

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References

19

The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

Bertram Pitt, Faı̈ez Zannad, Willem J. Remme et al. · New England Journal of Medicine · 1999 · 9.1K citations · Full text

, , +16

Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction

Bertram Pitt, Willem J. Remme, Faı̈ez Zannad et al. · New England Journal of Medicine · 2003 · 4.9K citations · Full text

, , +17

Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

Faı̈ez Zannad, John J.V. McMurray, Henry Krum et al. · New England Journal of Medicine · 2010 · 3.1K citations · Full text

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Lipophilicity in drug discovery

Michael J. Waring · Expert Opinion on Drug Discovery · 2010 · 844 citations

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Discovery of BAY 94‐8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases

Lars Bärfacker, Alexander Kühl, Alexander Hillisch et al. · ChemMedChem · 2012 · 264 citations

, , +14