Alexander Hillisch

Discovery of BAY 94‐8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases

Lars Bärfacker, Alexander Kühl, Alexander Hillisch et al. · ChemMedChem · 2012 · 264 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

A New Mode of Mineralocorticoid Receptor Antagonism by a Potent and Selective Nonsteroidal Molecule

Jérôme Fagart, Alexander Hillisch, J. Huyet et al. · Journal of Biological Chemistry · 2010 · 186 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1

Larbi Amazit, Florian Le Billan, Peter Kolkhof et al. · Journal of Biological Chemistry · 2015 · 181 citations · Full text

Life Sciences, Biochemistry, Endocrinology +15

The Lab Oddity Prevails: Discovery of Pan‐CDK Inhibitor (<i>R</i>)‐<i>S</i>‐Cyclopropyl‐<i>S</i>‐(4‐{[4‐{[(1<i>R</i>,2<i>R</i>)‐2‐hydroxy‐1‐methylpropyl]oxy}‐5‐(trifluoromethyl)pyrimidin‐2‐yl]amino}phenyl)sulfoximide (BAY 1000394) for the Treatment of Cancer

Ulrich Lücking, Rolf Jautelat, Martin Krüger et al. · ChemMedChem · 2013 · 178 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Binding Free Energy Calculations for Lead Optimization: Assessment of Their Accuracy in an Industrial Drug Design Context

Nadine Homeyer, Friederike Stoll, Alexander Hillisch et al. · Journal of Chemical Theory and Computation · 2014 · 177 citations

Pharmacy, Chemistry, Medicinal Chemistry +17