Warren J. Porter

Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain

Harry F. Dovey, Varghese John, J. P. Anderson et al. · Journal of Neurochemistry · 2001 · 877 citations · Full text

Protein Secretion, Neurochemical Biomarkers, Amyloid Precursor Protein +17

Substituted 3-Imidazo[1,2-<i>a</i>]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino- [6,7,1-<i>hi</i>]indol-7-yl)pyrrole-2,5-diones as Highly Selective and Potent Inhibitors of Glycogen Synthase Kinase-3

Thomas A. Engler, James R. Henry, Sushant Malhotra et al. · Journal of Medicinal Chemistry · 2004 · 100 citations · Full text

Insulin Receptor, Pharmaceutical Chemistry, Insulin Signaling +18

Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism

Akihiko Kato, Kevin D. Burris, Kevin M. Gardinier et al. · Nature Medicine · 2016 · 88 citations · Full text

Synaptic Transmission, Neurotransmitter, Neuromodulation Therapies +18

Neurochemical and behavioral profiling of the selective GlyT1 inhibitors ALX5407 and LY2365109 indicate a preferential action in caudal vs. cortical brain areas

Kenneth W. Perry, Julie F. Falcone, Matthew Fell et al. · Neuropharmacology · 2008 · 82 citations

Cortical Brain Areas, Neurotransmitter, Psychopharmacology +16

The development of potent and selective bisarylmaleimide GSK3 inhibitors

Thomas A. Engler, Sushant Malhotra, Timothy P. Burkholder et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 60 citations · Full text

Medicinal Chemistry, Medicine, Pharmacotherapy +5