Kevin M. Gardinier

New Chemical Modalities and Strategic Thinking in Early Drug Discovery

Marı́a-Jesús Blanco, Kevin M. Gardinier · ACS Medicinal Chemistry Letters · 2020 · 123 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism

Akihiko Kato, Kevin D. Burris, Kevin M. Gardinier et al. · Nature Medicine · 2016 · 90 citations · Full text

Life Sciences, Neuroscience, Pharmacology +16

Enforced Helicity: Efficient Access to Self-Organized Helical Molecular Strands by the Imine Route

Kevin M. Gardinier, R.G. Khoury, Jean‐Maríe Lehn · Chemistry - A European Journal · 2000 · 84 citations

Natural Sciences, Chemistry, Medicinal Chemistry +15

Perampanel, an Antagonist of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptors, for the Treatment of Epilepsy: Studies in Human Epileptic Brain and Nonepileptic Brain and in Rodent Models

Ruud Zwart, Emanuele Sher, Xingjie Ping et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 69 citations

Medicine, Neuroscience, Pharmacology +14

Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8

Kevin M. Gardinier, Douglas L. Gernert, Warren J. Porter et al. · Journal of Medicinal Chemistry · 2016 · 60 citations · Full text

Medicine, Neuroscience, Pharmacology +17