Concepedia

The development of potent and selective bisarylmaleimide GSK3 inhibitors

Thomas A. Engler, Sushant Malhotra, Timothy P. Burkholder, James R. Henry, David Mendel, Warren J. Porter, Kelly Furness, Clive Diefenbacher, Angela L. Marquart, Jon K. Reel,

Bioorganic & Medicinal Chemistry Letters · 2005 · 62 citations · 29 references

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29

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Darren A.E. Cross, Dario R. Alessi, Philip Cohen et al. · Nature · 1995 · 5.2K citations

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Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

Matthew P. Coghlan, Ainsley A. Culbert, Darren A.E. Cross et al. · Chemistry & Biology · 2000 · 895 citations · Full text

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Selective Glycogen Synthase Kinase 3 Inhibitors Potentiate Insulin Activation of Glucose Transport and Utilization In Vitro and In Vivo

David B. Ring, Kirk W. Johnson, Erik J. Henriksen et al. · Diabetes · 2003 · 555 citations · Full text

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Structural Basis for the Synthesis of Indirubins as Potent and Selective Inhibitors of Glycogen Synthase Kinase-3 and Cyclin-Dependent Kinases

Panagiotis Polychronopoulos, Prokopios Magiatis, Alexios‐Léandros Skaltsounis et al. · Journal of Medicinal Chemistry · 2004 · 376 citations · Full text

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Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes.

Svetlana E. Nikoulina, Theodore P. Ciaraldi, Sunder Mudaliar et al. · Diabetes · 2000 · 352 citations · Full text

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