Timothy P. Burkholder

Author

Also Known As

T P Burkholder, T. P. BURKHOLDER, T. P. Burkholder, T.P. Burkholder, Timothy Burkholder, Timothy P Burkholder, Timothy P. Burkholder

Publications

945

Citations

H-Index

Concepts

All Affiliations

Eli Lilly (United States)The Ohio State University at Marion

About

Timothy P. Burkholder is an author at Eli Lilly (United States) specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	558
2	Natural Sciences	8	8	536
3	Biochemistry	6	6	453
4	Biomolecular Engineering	4	4	152
5	Engineering	3	3	99

Timothy P. Burkholder

Publications

918

Citations

H-Index

Page 1

	Year	Citations
Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells Bo Tan, Debra A. Young, Zhao-Hai Lu, Journal of Biological Chemistry GlycobiologyNad+ BiosynthesisMetabolic RemodelingPharmacological InhibitionSerine Biosynthesis	2012	173
Substituted 3-Imidazo[1,2-<i>a</i>]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino- [6,7,1-<i>hi</i>]indol-7-yl)pyrrole-2,5-diones as Highly Selective and Potent Inhibitors of Glycogen Synthase Kinase-3 Thomas A. Engler, James R. Henry, Sushant Malhotra, Journal of Medicinal Chemistry Insulin ReceptorPharmaceutical ChemistryInsulin SignalingType Ii DiabetesMolecular Pharmacology	2004	100
Synthesis via vinyl sulfones. 38. Total synthesis of the cephalotaxus alkaloids dl-cephalotaxine, dl-11-hydroxycephalotaxine, and dl-drupacine Timothy P. Burkholder, Phillip L. Fuchs Journal of the American Chemical Society Natural Product SynthesisBioorganic ChemistryBiochemistryNatural SciencesMedicine	1990	75
Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F Liandong Ma, Joshua R. Clayton, Richard A. Walgren, Blood Cancer Journal	2013	64
Synthesis via vinyl sulfones. 27. Total synthesis of cephalotaxine. The first example of an intramolecular [4 + 2] cycloaddition where the dienophile has been delivered from the face opposite to the tethering moiety Timothy P. Burkholder, P. L. Fuchs Journal of the American Chemical Society Bioorganic ChemistryEngineeringFace OppositeHeterocyclicNatural Sciences	1988	60
The development of potent and selective bisarylmaleimide GSK3 inhibitors Thomas A. Engler, Sushant Malhotra, Timothy P. Burkholder, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryMedicinePharmacotherapyAnti-cancer AgentDrug Development	2005	60
Development and a Practical Synthesis of the JAK2 Inhibitor LY2784544 David Mitchell, Kevin P. Cole, Patrick M. Pollock, Organic Process Research & Development Route SelectionOrganic ChemistryChemical BiologyRoute Selection ConsiderationsPharmaceutical Chemistry	2011	53
Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration Genshi Zhao, Colin F. Green, Yu‐Hua Hui, Molecular Cancer Therapeutics	2017	45
An acyliminium ion route to and “Anti” phe-gly dipeptide mimetics Gary A. Flynn, Timothy P. Burkholder, Edward W. Huber, Bioorganic & Medicinal Chemistry Letters Acyliminium Ion RouteBiochemistryNatural SciencesOrganic ChemistryChemistry	1991	36
Effect of MDL 105,212, a nonpeptide NK-1/NK-2 receptor antagonist in an allergic guinea pig model. Elizabeth M. Kudlacz, Robert W. Knippenberg, Deborah E. Logan, Journal of Pharmacology and Experimental Therapeutics	1996	35

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