Jerry Meng

Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)

J. Jean Cui, Michelle Tran‐Dubé, Hong Shen et al. · Journal of Medicinal Chemistry · 2011 · 922 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Crystal Structure of Human ABAD/HSD10 with a Bound Inhibitor: Implications for Design of Alzheimer's Disease Therapeutics

Charles R. Kissinger, Paul A. Rejto, Laura A. Pelletier et al. · Journal of Molecular Biology · 2004 · 99 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +10

Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone

Pei‐Pei Kung, Lee Funk, Jerry Meng et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 53 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Optimization of Potent, Selective, and Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors of Heat Shock Protein 90. Identification of Development Candidate 2-Amino-4-{4-chloro-2-[2-(4-fluoro-1<i>H</i>-pyrazol-1-yl)ethoxy]-6-methylphenyl}-<i>N</i>-(2,2-difluoropropyl)-5,7-dihydro-6<i>H</i>-pyrrolo[3,4-<i>d</i>]pyrimidine-6-carboxamide

Luke R. Zehnder, Michael J. Bennett, Jerry Meng et al. · Journal of Medicinal Chemistry · 2011 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design, synthesis, and biological evaluation of novel human 5′-deoxy-5′-methylthioadenosine phosphorylase (MTAP) substrates

Pei‐Pei Kung, Luke R. Zehnder, Jerry Meng et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 21 citations

Pharmacy, Biochemistry, Medicinal Chemistry +14