Eugenia Petoukhov

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Amber L. Southwell, Niels H. Skotte, Holly Kordasiewicz et al. · Molecular Therapy · 2014 · 145 citations · Full text

An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes

Amber L. Southwell, Amy Smith-Dijak, Chris Kay et al. · Human Molecular Genetics · 2016 · 136 citations · Full text

Neurogenomics, Genetics, Molecular Biology +22

Allele-Specific Suppression of Mutant Huntingtin Using Antisense Oligonucleotides: Providing a Therapeutic Option for All Huntington Disease Patients

Niels H. Skotte, Amber L. Southwell, Michael E. Østergaard et al. · PLoS ONE · 2014 · 112 citations · Full text

Engineering, Genetics, Molecular Biology +17

Activity-dependent secretion of progranulin from synapses

Eugenia Petoukhov, Sarah Fernando, Fergil Mills et al. · Journal of Cell Science · 2013 · 52 citations · Full text

Protein Secretion, Synapse Formation, Neurotransmitter +18

A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles

Amber L. Southwell, Niels H. Skotte, Erika B. Villanueva et al. · Human Molecular Genetics · 2017 · 36 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Transgenic Mouse Models +13