Concepedia

Erika B. Villanueva

EB

15

Publications

1.2K

Citations

15

H-Index

2007

Active since

Affiliations

University of British Columbia(Current)

Child and Family Research Institute

Okanagan University College

Ionis Pharmaceuticals (United States)

Western Washington University

Erika B. Villanueva is an author at University of British Columbia specializing in medicine, pharmacology, and drug discovery.

ORCID

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Publications per year

2007–2018

15

Publications

15

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

Michael E. Østergaard, Amber L. Southwell, Holly Kordasiewicz et al. · Nucleic Acids Research · 2013 · 158 citations · Full text

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Amber L. Southwell, Niels H. Skotte, Holly Kordasiewicz et al. · Molecular Therapy · 2014 · 145 citations · Full text

An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes

Amber L. Southwell, Amy Smith-Dijak, Chris Kay et al. · Human Molecular Genetics · 2016 · 136 citations · Full text

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Huntingtin suppression restores cognitive function in a mouse model of Huntington’s disease

Amber L. Southwell, Holly Kordasiewicz, Douglas R. Langbehn et al. · Science Translational Medicine · 2018 · 122 citations

A fully humanized transgenic mouse model of Huntington disease

Amber L. Southwell, Simon C. Warby, Jeffrey B. Carroll et al. · Human Molecular Genetics · 2012 · 106 citations · Full text

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