Athiwat Hutchaleelaha

A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa

Genmin Lu, Francis DeGuzman, Stanley J. Hollenbach et al. · Nature Medicine · 2013 · 697 citations

Medicine, Hematology, Pharmacology +16

<scp>GBT</scp>440 increases haemoglobin oxygen affinity, reduces sickling and prolongs <scp>RBC</scp> half‐life in a murine model of sickle cell disease

Donna Oksenberg, Kobina Dufu, Mira Patel et al. · British Journal of Haematology · 2016 · 235 citations · Full text

Medicine, Hematology, Pharmacokinetics +17

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

Brian Metcalf, Chih-Yuan Chuang, Kobina Dufu et al. · ACS Medicinal Chemistry Letters · 2017 · 190 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial Demonstrating Reversal Of Rivaroxaban-Induced Anticoagulation In Healthy Subjects By Andexanet Alfa (PRT064445), An Antidote For Fxa Inhibitors

Mark Crowther, M. Manasar.Vandana, Michael Kitt et al. · Blood · 2013 · 115 citations

Medicine, Pharmacology, Pharmacotherapy +14

Identification of Orally Active, Potent, and Selective 4-Piperazinylquinazolines as Antagonists of the Platelet-Derived Growth Factor Receptor Tyrosine Kinase Family

Anjali Pandey, Deborah L. Volkots, J. Seroogy et al. · Journal of Medicinal Chemistry · 2002 · 114 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15