Francis DeGuzman

A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa

Genmin Lu, Francis DeGuzman, Stanley J. Hollenbach et al. · Nature Medicine · 2013 · 689 citations

Thrombosis, Venous Thrombosis, Cardiovascular Disease +13

P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries

Patrick André, Suzanne M. Delaney, Thomas J. LaRocca et al. · Journal of Clinical Investigation · 2003 · 347 citations · Full text

Integrin cytoplasmic tyrosine motif is required for outside-in αIIbβ3 signalling and platelet function

Debbie A. Law, Francis DeGuzman, Patrick W. Heiser et al. · Nature · 1999 · 317 citations

Signal Transduction, Signaling Pathway, Blood Platelet +11

A thrombin receptor function for platelet glycoprotein Ib–IX unmasked by cleavage of glycoprotein V

Vanitha Ramakrishnan, Francis DeGuzman, Ming Bao et al. · Proceedings of the National Academy of Sciences · 2001 · 170 citations

Immunology, Protease Thrombin, Thrombosis +18

PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model

Michael P. Reilly, Uma Sinha, Pierrette André et al. · Blood · 2010 · 131 citations · Full text