Sabin Llona‐Minguez

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

Brent D. G. Page, Nicholas C.K. Valerie, Roni H. G. Wright et al. · Nature Communications · 2018 · 124 citations · Full text

Medicine, Molecular Biology, Oncology +16

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Nadilly Bonagas, Nina Gustafsson, Martin Henriksson et al. · Nature Cancer · 2022 · 105 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Robert Gustafsson, Ann‐Sofie Jemth, Nina Gustafsson et al. · Cancer Research · 2016 · 99 citations

Medicine, Oncology, Pharmacology +13

Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1

Sabin Llona‐Minguez, Andreas Höglund, Sylvain A. Jacques et al. · Journal of Medicinal Chemistry · 2016 · 49 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers

Nahoum G. Anthony, Jessica Baiget, Giacomo Berretta et al. · Journal of Medicinal Chemistry · 2017 · 38 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13