Concepedia

Martin Henriksson

MH

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Publications

11

Citations

1.2K

H-Index

11

Active since

2007

Affiliations

Science for Life Laboratory(Current)

Karolinska Institutet

Stockholm University

University of Sheffield

Uppsala University

Martin Henriksson is an author at Science for Life Laboratory specializing in oncology, molecular oncology, and drug discovery.

ORCID

Publications per year

2007–2023

11

Publications

11

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Helge Gad, Tobias Koolmeister, Ann‐Sofie Jemth et al. · Nature · 2014 · 529 citations

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Validation and development of MTH1 inhibitors for treatment of cancer

Ulrika Warpman Berglund, Kumar Sanjiv, Helge Gad et al. · Annals of Oncology · 2016 · 145 citations · Full text

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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Nadilly Bonagas, Nina Gustafsson, Martin Henriksson et al. · Nature Cancer · 2022 · 105 citations · Full text

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Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

Robert Gustafsson, Ann‐Sofie Jemth, Nina Gustafsson et al. · Cancer Research · 2016 · 99 citations

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Discovery of a Potent, Orally Active 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor for Clinical Study: Identification of (<i>S</i>)-2-((1<i>S</i>,2<i>S</i>,4<i>R</i>)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5<i>H</i>)-one (AMG 221)

Murielle M. Véniant, Clarence Hale, Randall W. Hungate et al. · Journal of Medicinal Chemistry · 2010 · 82 citations · Full text

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