Celia R. Berkers

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

Oliver D.K. Maddocks, Celia R. Berkers, Susan Mason et al. · Nature · 2012 · 1K citations

Life Sciences, Cancer Biology, Oncology +16

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

Dharminder Chauhan, Laurence Catley, Guilan Li et al. · Cancer Cell · 2005 · 698 citations · Full text

Medicine, Oncology, Pharmacology +14

Crystal Structure of the Boronic Acid-Based Proteasome Inhibitor Bortezomib in Complex with the Yeast 20S Proteasome

M. Groll, Celia R. Berkers, Hidde L. Ploegh et al. · Structure · 2006 · 471 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Molecular basis of bortezomib resistance: proteasome subunit β5 (PSMB5) gene mutation and overexpression of PSMB5 protein

Ruud Oerlemans, N. Franke, Yehuda G. Assaraf et al. · Blood · 2008 · 449 citations

Life Sciences, Biochemistry, Molecular Biology +13

Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity

Jorg van Loosdregt, Veerle Fleskens, Juan Fu et al. · Immunity · 2013 · 311 citations · Full text

Life Sciences, Immunology, Molecular Biology +9