Oliver D.K. Maddocks

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

Oliver D.K. Maddocks, Celia R. Berkers, Susan Mason et al. · Nature · 2012 · 1K citations

Reductive Stress, Tumor Biology, Systems Biology +13

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

Barbara Chaneton, Petra Hillmann, Liang Zheng et al. · Nature · 2012 · 647 citations · Full text

Pyruvate Kinase M2, Natural Ligand, Signal Transduction +10

Modulating the therapeutic response of tumours to dietary serine and glycine starvation

Oliver D.K. Maddocks, Dimitris Athineos, Eric C. Cheung et al. · Nature · 2017 · 598 citations

Tumor Biology, Dietary Serine, Chemoprevention Strategy +11

Serine, but Not Glycine, Supports One-Carbon Metabolism and Proliferation of Cancer Cells

Christiaan F. Labuschagne, Niels J. F. van den Broek, Gillian Mackay et al. · Cell Reports · 2014 · 576 citations · Full text

Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells

Oliver D.K. Maddocks, Christiaan F. Labuschagne, Peter D. Adams et al. · Molecular Cell · 2016 · 419 citations · Full text