Laurence Catley

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

Dharminder Chauhan, Laurence Catley, Guilan Li et al. · Cancer Cell · 2005 · 698 citations · Full text

Medicine, Oncology, Pharmacology +14

Aggresome induction by proteasome inhibitor bortezomib and α-tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells

Laurence Catley, Ellen Weisberg, Tanyel Kiziltepe et al. · Blood · 2006 · 340 citations · Full text

Medicine, Oncology, Pharmacology +17

Role of B-Cell–Activating Factor in Adhesion and Growth of Human Multiple Myeloma Cells in the Bone Marrow Microenvironment

Yu‐Tzu Tai, Xianfeng Li, Iris Breitkreutz et al. · Cancer Research · 2006 · 242 citations

Life Sciences, Cell Biology, Molecular Biology +17

Insulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of beta1-integrin and phosphatidylinositol 3'-kinase/AKT signaling.

Yu‐Tzu Tai, Klaus Podar, Laurence Catley et al. · PubMed · 2003 · 190 citations

Life Sciences, Cell Biology, Cell Adhesion +16

Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells

Teru Hideshima, Laurence Catley, Noopur Raje et al. · British Journal of Haematology · 2007 · 102 citations · Full text

Medicine, Oncology, Pharmacology +17