Patrick M. Helbling

Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization

Chiara Baccin, Jude Al-Sabah, Lars Velten et al. · Nature Cell Biology · 2019 · 857 citations · Full text

Cell Lineage, Developmental Biology, Functional Genomics +11

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Mohsen Malehmir, Dominik Pfister, Suchira Gallage et al. · Nature Medicine · 2019 · 360 citations · Full text

Hepatology, Medicine, Liver Physiology +9

Quantitative spatial analysis of haematopoiesis-regulating stromal cells in the bone marrow microenvironment by 3D microscopy

Álvaro Gomariz, Patrick M. Helbling, Stephan Isringhausen et al. · Nature Communications · 2018 · 155 citations · Full text

IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice

Larisa V. Kovtonyuk, Francisco Caiado, Santiago García‐Martín et al. · Blood · 2021 · 139 citations · Full text

Lymphocyte Development, Immune Regulation, Immunology +18

Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation

Patrick M. Helbling, Elena Piñeiro-Yáñez, Rahel Gerosa et al. · Cell Reports · 2019 · 120 citations · Full text

Inflammation, Developmental Biology, Single Cell Sequencing +11