Larisa V. Kovtonyuk

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal

Eric M. Pietras, Cristina Mirantes-Barbeito, Sarah Fong et al. · Nature Cell Biology · 2016 · 705 citations

Life Sciences, Cell Biology, Immunology +16

Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness

Hitoshi Takizawa, Kristin Fritsch, Larisa V. Kovtonyuk et al. · Cell stem cell · 2017 · 280 citations · Full text

Life Sciences, Cell Biology, Immunology +15

Microbiota-Derived Compounds Drive Steady-State Granulopoiesis via MyD88/TICAM Signaling

Maria L. Balmer, Christian M. Schürch, Yasuyuki Saito et al. · The Journal of Immunology · 2014 · 264 citations

Veterinary Medicine, Immunology, Host-pathogen Interactions +10

IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice

Larisa V. Kovtonyuk, Francisco Caiado, Santiago García‐Martín et al. · Blood · 2021 · 152 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Aging drives <i>Tet2</i> <i>+/−</i> clonal hematopoiesis via IL-1 signaling

Francisco Caiado, Larisa V. Kovtonyuk, Nagihan G. Gonullu et al. · Blood · 2022 · 150 citations · Full text

Life Sciences, Genetics, Hematology +17