Betty Jin

Rational design of potent sialidase-based inhibitors of influenza virus replication

Mark von Itzstein, Wen‐Yang Wu, Gaik B. Kok et al. · Nature · 1993 · 1.8K citations

Rational Design, Medicine, Antiviral Therapy +6

Inhibition of sialidases from viral, bacterial and mammalian sources by analogues of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid modified at the C-4 position

Cindy T. Holzer, Mark von Itzstein, Betty Jin et al. · Glycoconjugate Journal · 1993 · 152 citations

C-4 Position, Medicine, Mammalian Sources +8

The synthesis of 2,3-didehydro-2,4-dideoxy-4-guanidinyl-N-acetylneuraminic acid: a potent influenza virus sialidase inhibitor

Mark von Itzstein, Wen‐Yang Wu, Betty Jin · Carbohydrate Research · 1994 · 148 citations

Medicinal Chemistry, Medicine, 2,3-Didehydro-2,4-dideoxy-4-guanidinyl-n-acetylneuraminic Acid +7

Dimeric Zanamivir Conjugates with Various Linking Groups Are Potent, Long-Lasting Inhibitors of Influenza Neuraminidase Including H5N1 Avian Influenza

Simon J. F. Macdonald, Rachel Cameron, Derek A. Demaine et al. · Journal of Medicinal Chemistry · 2005 · 87 citations · Full text

Medicinal Chemistry, Medicine, Plaque Reduction Assays +14

Potent and Long-Acting Dimeric Inhibitors of Influenza Virus Neuraminidase Are Effective at a Once-Weekly Dosing Regimen

Simon J. F. Macdonald, Keith G. Watson, Rachel Cameron et al. · Antimicrobial Agents and Chemotherapy · 2004 · 80 citations · Full text

Medicinal Chemistry, Antiviral Compound, Medicine +12