Gaik B. Kok

Rational design of potent sialidase-based inhibitors of influenza virus replication

Mark von Itzstein, Wen‐Yang Wu, Gaik B. Kok et al. · Nature · 1993 · 1.8K citations

Rational Design, Medicine, Antiviral Therapy +6

A Study of the Active Site of Influenza Virus Sialidase:  An Approach to the Rational Design of Novel Anti-influenza Drugs

Mark von Itzstein, Jeffrey C. Dyason, Stuart W. Oliver et al. · Journal of Medicinal Chemistry · 1996 · 116 citations

Bioorganic Chemistry, Antiviral Drug, Chemical Biology +16

Two-Step Iron(0)-Mediated N-Demethylation of <i>N</i>-Methyl Alkaloids

Gaik B. Kok, Cory C. Pye, Robert D. Singer et al. · The Journal of Organic Chemistry · 2010 · 57 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Bioorganic Chemistry +14

Synthesis and biological evaluation of sulfur isosters of the potent influenza virus sialidase inhibitors 4-amino-4-deoxy- and 4-deoxy-4-guanidino-Neu5Ac2en

Gaik B. Kok, Michael G. Campbell, Brendan L. Mackey et al. · Journal of the Chemical Society Perkin Transactions 1 · 1996 · 39 citations

Bioorganic Chemistry, Organic Chemistry, Chemistry +19

An Improved Process for the N‐Demethylation of Opiate Alkaloids using an Iron(II) Catalyst in Acetate Buffer

Gaik B. Kok, Trent D. Ashton, Peter J. Scammells · Advanced Synthesis & Catalysis · 2009 · 37 citations

Pharmaceutical Science, Bioorganic Chemistry, N‐demethylate Opiate Alkaloids +19