Wen‐Yang Wu

Rational design of potent sialidase-based inhibitors of influenza virus replication

Mark von Itzstein, Wen‐Yang Wu, Gaik B. Kok et al. · Nature · 1993 · 1.8K citations

Rational Design, Medicine, Antiviral Therapy +6

4D printing of mechanically robust PLA/TPU/Fe3O4 magneto-responsive shape memory polymers for smart structures

Han Liu, Feifan Wang, Wen‐Yang Wu et al. · Composites Part B Engineering · 2022 · 184 citations

Materials Science, Smart Structures, Engineering +6

Inhibition of sialidases from viral, bacterial and mammalian sources by analogues of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid modified at the C-4 position

Cindy T. Holzer, Mark von Itzstein, Betty Jin et al. · Glycoconjugate Journal · 1993 · 152 citations

C-4 Position, Medicine, Mammalian Sources +8

The synthesis of 2,3-didehydro-2,4-dideoxy-4-guanidinyl-N-acetylneuraminic acid: a potent influenza virus sialidase inhibitor

Mark von Itzstein, Wen‐Yang Wu, Betty Jin · Carbohydrate Research · 1994 · 148 citations

Medicinal Chemistry, Medicine, 2,3-Didehydro-2,4-dideoxy-4-guanidinyl-n-acetylneuraminic Acid +7

A Study of the Active Site of Influenza Virus Sialidase:  An Approach to the Rational Design of Novel Anti-influenza Drugs

Mark von Itzstein, Jeffrey C. Dyason, Stuart W. Oliver et al. · Journal of Medicinal Chemistry · 1996 · 116 citations

Bioorganic Chemistry, Antiviral Drug, Chemical Biology +16