William J. Pitts

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

Margaret Favata, Kurumi Y. Horiuchi, Elizabeth J. Manos et al. · Journal of Biological Chemistry · 1998 · 3K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +13

Practical olefin hydroamination with nitroarenes

Jinghan Gui, Chung‐Mao Pan, Ying Jin et al. · Science · 2015 · 533 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

MEK inhibitors: The chemistry and biological activity of U0126, its analogs, and cyclization products

John V. Duncia, Joseph B. Santella, C. Anne Higley et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 406 citations · Full text

Life Sciences, Biochemistry, Pharmacology +11

The Immunosuppressive Metabolite of Leflunomide Is a Potent Inhibitor of Human Dihydroorotate Dehydrogenase

June P. Davis, Gary A. Cain, William J. Pitts et al. · Biochemistry · 1996 · 294 citations

Medicine, Biochemistry, Pharmacology +13

Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain

John S. Tokarski, Adriana Zupa-Fernandez, Jeffrey Tredup et al. · Journal of Biological Chemistry · 2015 · 116 citations · Full text

Life Sciences, Immunology, Pharmacology +17