Jeffrey Tredup

Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165

Stephen T. Wrobleski, Ryan Moslin, Shuqun Lin et al. · Journal of Medicinal Chemistry · 2019 · 345 citations · Full text

Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain

John S. Tokarski, Adriana Zupa-Fernandez, Jeffrey Tredup et al. · Journal of Biological Chemistry · 2015 · 112 citations · Full text

The Discovery of Asunaprevir (BMS-650032), An Orally Efficacious NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Paul M. Scola, Li‐Qiang Sun, Alan Xiangdong Wang et al. · Journal of Medicinal Chemistry · 2014 · 109 citations

2-Aryl-2,2-difluoroacetamide FKBP12 Ligands:  Synthesis and X-ray Structural Studies

Gene M. Dubowchik, Vivekananda M. Vrudhula, Bireshwar Dasgupta et al. · Organic Letters · 2001 · 103 citations

Chemical Biology, X-ray Structural Studies, Halogenation +15

Identification of <i>N</i>-Methyl Nicotinamide and <i>N</i>-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)

Ryan Moslin, Yanlei Zhang, Stephen T. Wrobleski et al. · Journal of Medicinal Chemistry · 2019 · 84 citations · Full text