Bang-Lin Wan

Discovery of Vaniprevir (MK-7009), a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor

John A. McCauley, Charles McIntyre, Michael T. Rudd et al. · Journal of Medicinal Chemistry · 2010 · 177 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Molecular Modeling Based Approach to Potent P2−P4 Macrocyclic Inhibitors of Hepatitis C NS3/4A Protease

Nigel J. Liverton, M. Katharine Holloway, John A. McCauley et al. · Journal of the American Chemical Society · 2008 · 135 citations

Pharmacy, Medicinal Chemistry, Pharmacokinetics +17

Discovery of 3-{5-[(6-Amino-1<i>H</i>-pyrazolo[3,4-<i>b</i>]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor with Improved Potency against Key Mutant Viruses

Thomas J. Tucker, John T. Sisko, Robert M. Tynebor et al. · Journal of Medicinal Chemistry · 2008 · 133 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations

Thomas J. Tucker, Sandeep Saggar, John T. Sisko et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 61 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Non-peptide calcitonin gene-related peptide receptor antagonists from a benzodiazepinone lead

Theresa M. Williams, Craig A. Stump, Diem N. Nguyen et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 52 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +9