Yoshiaki Nabuchi

Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization

Tomoyuki Igawa, Shinya Ishii, Tatsuhiko Tachibana et al. · Nature Biotechnology · 2010 · 351 citations

Pharmacy, Biotechnology, Immunology +13

Identification and Multidimensional Optimization of an Asymmetric Bispecific IgG Antibody Mimicking the Function of Factor VIII Cofactor Activity

Zenjiro Sampei, Tomoyuki Igawa, Tetsuhiro Soeda et al. · PLoS ONE · 2013 · 325 citations · Full text

Pharmacy, Biotechnology, Medicinal Chemistry +17

Reduced elimination of IgG antibodies by engineering the variable region

Tomoyuki Igawa, Hiroyuki Tsunoda, Tatsuhiko Tachibana et al. · Protein Engineering Design and Selection · 2010 · 262 citations

Pharmacy, Immunology, Pharmacokinetics +17

Prediction of human intestinal permeability using artificial membrane permeability

Kiyohiko Sugano, Yoshiaki Nabuchi, Minoru Machida et al. · International Journal of Pharmaceutics · 2003 · 112 citations

Pharmacy, Biomedical Engineering, Physiology +12

Correction of Permeability with Pore Radius of Tight Junctions in Caco-2 Monolayers Improves the Prediction of the Dose Fraction of Hydrophilic Drugs Absorbed by Humans

Ryoichi Saitoh, Kiyohiko Sugano, Noriyuki Takata et al. · Pharmaceutical Research · 2004 · 83 citations

Pharmacy, Pharmacokinetics, Pharmacology +16