John Manis

Plasma cell differentiation requires the transcription factor XBP-1

Andreas Reimold, Neal N. Iwakoshi, John Manis et al. · Nature · 2001 · 1.3K citations

Transcriptional Regulation, Developmental Biology, Cell Regulation +6

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

Hwei-Ling Cheng, Raúl Mostoslavsky, Shinichi Saito et al. · Proceedings of the National Academy of Sciences · 2003 · 1.1K citations · Full text

Sirt1 Function, Genetics, Apoptosis +19

MDC1 Maintains Genomic Stability by Participating in the Amplification of ATM-Dependent DNA Damage Signals

Zhenkun Lou, Katherine Minter‐Dykhouse, Sonia Franco et al. · Molecular Cell · 2006 · 615 citations · Full text

Chromatin, Genome Instability, Dna Damage +8

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

Yijie Gao, David O. Ferguson, Wei Xie et al. · Nature · 2000 · 581 citations

Tumor Biology, Genome Instability, Chromatin +12

IgH class switching and translocations use a robust non-classical end-joining pathway

Catherine T. Yan, Cristian Boboilă, Ellen Kris Souza et al. · Nature · 2007 · 570 citations

Igh Class Switching, Molecular Biology, Systems Biology