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MDC1 Maintains Genomic Stability by Participating in the Amplification of ATM-Dependent DNA Damage Signals

Zhenkun Lou, Katherine Minter‐Dykhouse, Sonia Franco, Monica Gostissa, Melissa A. Rivera, Arkady Celeste, John Manis, Jan van Deursen, André Nussenzweig, Tanya T. Paull,

Molecular Cell · 2006 · 620 citations · 41 references

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41

DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

Emmy P. Rogakou, Duane R. Pilch, Ann H. Orr et al. · Journal of Biological Chemistry · 1998 · 5.4K citations · Full text

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Christopher J. Bakkenist, Michael B. Kastan · Nature · 2003 · 3.4K citations

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Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo

Emmy P. Rogakou, Chye Boon, Christophe E. Redon et al. · The Journal of Cell Biology · 1999 · 2.4K citations · Full text

, , +17

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

Tanya T. Paull, Emmy P. Rogakou, Vikky Yamazaki et al. · Current Biology · 2000 · 2.1K citations · Full text

, , +17

ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks

Sandeep Burma, Benjamin P. Chen, Michael Murphy et al. · Journal of Biological Chemistry · 2001 · 1.9K citations · Full text

, , +17