DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

Emmy P. Rogakou, Duane R. Pilch, Ann H. Orr, +2

Journal of Biological Chemistry

Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo

Emmy P. Rogakou, Chye Boon, Christophe E. Redon, +1

The Journal of Cell Biology

Megabase ChromatinDna DamageGeneticsRadiation EffectRadiation Exposure +20

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

Tanya T. Paull, Emmy P. Rogakou, Vikky Yamazaki, +3

Current Biology

Histone ModificationsDna DamageEpigenetic ChangeGeneticsMolecular Biology +14

Recombinational DNA double-strand breaks in mice precede synapsis

Shantha K. Mahadevaiah, James M. A. Turner, Frédéric Baudat, +7

Nature Genetics

Knockout MouseGenome InstabilityMolecular NeuroscienceMice Precede SynapsisGenetics +5

Initiation of DNA Fragmentation during Apoptosis Induces Phosphorylation of H2AX Histone at Serine 139

Emmy P. Rogakou, Wilberto Nieves‐Neira, Chye Boon, +2

Journal of Biological Chemistry

Quantitative Detection of¹²⁵IdU-Induced DNA Double-Strand Breaks with γ-H2AX Antibody

Olga A. Sedelnikova, Emmy P. Rogakou, Igor G. Panyutin, +1

Radiation Research

Dna DamageEngineeringRadiation EffectImmunologyDna Analysis +17

Phosphorylation of Histone H2AX and Activation of Mre11, Rad50, and Nbs1 in Response to Replication-dependent DNA Double-strand Breaks Induced by Mammalian DNA Topoisomerase I Cleavage Complexes

Takahisa Furuta, Haruyuki Takemura, Zhi-Yong Liao, +11

Journal of Biological Chemistry

Response to RAG-Mediated V(D)J Cleavage by NBS1 and γ-H2AX

Hua Tang Chen, Avinash Bhandoola, Michael J. Difilippantonio, +8

Science

Dna DamageImmunologyMolecular BiologyImmunotherapyGenetic Disorders +14

Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint‐blind DNA damage

Christophe E. Redon, Duane R. Pilch, Emmy P. Rogakou, +3

EMBO Reports

Histone ModificationsChromatinGenome InstabilitySerine 129Checkpoint‐blind Dna Damage +12

Histone variants of H2A and H3 families are regulated during in vitro aging in the same manner as during differentiation

Emmy P. Rogakou, Kalliope E. Sekeri‐Pataryas

Experimental Gerontology

Histone ModificationsChromatinAgingChromatin RemodelingEpigenetic Change +9