Michael Zinda

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Michael Hedvat, Dennis Huszar, Andreas Herrmann et al. · Cancer Cell · 2009 · 529 citations · Full text

Medicine, Oncology, Pharmacology +9

CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition

David Gallo, Jordan T.F. Young, Jimmy Fourtounis et al. · Nature · 2022 · 229 citations · Full text

Life Sciences, Genetics, Oncology +17

Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS

Sarah J. Ross, Alexey S. Revenko, Lyndsey Hanson et al. · Science Translational Medicine · 2017 · 182 citations

Medicine, Oncology, Pharmacology +16

AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies

Garrett W. Rhyasen, Maureen M. Hattersley, Yi Yao et al. · Molecular Cancer Therapeutics · 2016 · 157 citations · Full text

Medicine, Oncology, Pharmacology +17

AKT-1, -2, and -3 are expressed in both normal and tumor tissues of the lung, breast, prostate, and colon.

Michael Zinda, Mac Johnson, Joshua Paul et al. · PubMed · 2001 · 150 citations

Medicine, Molecular Biology, Oncology +15