Concepedia

Solene Dussauge

SD

Statistics

Publications

5

Citations

250

H-Index

5

Active since

2016

Affiliations

Novartis (Switzerland)(Current)

Novartis (United States)

Novartis Institutes for BioMedical Research

Solene Dussauge is an author at Novartis (Switzerland) specializing in medicinal chemistry, drug discovery, and enzyme inhibition.

Publications per year

2016–2022

5

Publications

5

JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRAS<sup>G12C</sup> for the Treatment of Solid Tumors

Edwige Lorthiois, Marc Gerspacher, Kim S. Beyer et al. · Journal of Medicinal Chemistry · 2022 · 95 citations · Full text

, , +17

Small-molecule factor D inhibitors targeting the alternative complement pathway

Jürgen Maibaum, Sha-Mei Liao, Anna Vulpetti et al. · Nature Chemical Biology · 2016 · 75 citations · Full text

, , +14

Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition <i>in Vivo</i>

Edwige Lorthiois, Karen Anderson, Anna Vulpetti et al. · Journal of Medicinal Chemistry · 2017 · 37 citations · Full text

, , +17

Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach

Edwige Lorthiois, James Roache, David Barnes‐Seeman et al. · Journal of Medicinal Chemistry · 2020 · 22 citations · Full text

, , +16

Discovery of New Fe(II)/α-Ketoglutarate-Dependent Dioxygenases for Oxidation of <scp>l</scp>-Proline

Erika Tassano, Charles M. Moore, Solene Dussauge et al. · Organic Process Research & Development · 2022 · 21 citations

, , +17

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